Project acronym: STRIKE
Project title: Comprehensive STRategies to tacKIE malignant tumors: from nanomedicine and theranostics to precision medicine / STRIKE
Project registration number: Grant agreement No 101072462
State funding provider: European Union
Programme: Horizon 2020
Start date: 2023-01-01
End date: 2026-12-31
Principal investigator: Dr. Francisco J Terán

Programme: Horizon / HORIZON-MSCA-2021-DN-01 

The project STRIKE will increase excellence in research and training in nanomedicine medicine creating a new generation of entrepreneurial and innovative multidisciplinary researchers. New experimental aspects on design and synthesis of nanostructured magnetic materials will be applied to the development of innovative magnetic field-responsive nanoterapheutics for osteosarcoma (OS) combinational therapy. Moreover, the peculiar features of STRIKE nanomaterials will be exploited for liquid biopsy using biological samples of BRCA+ breast cancer (BC) patients. The cooperation among outstanding universities, research institutes and industries will provide the ESRs with trans-national exchanges and the most innovative research trainings in novel anticancer therapeutic strategies, including in vivo biological evaluation, imaging in OS and early diagnosis in breast cancer. STRIKE will provide enhanced career perspectives in academic and non-academic sectors for eight PhD students in highly innovative fields by interdisciplinary mobility among institutes and companies in eight European countries.

STRIKE aims to:  

  1. develop eight highly skilled employable researchers;
  2. enhance interdisciplinary capacity and cooperation within the EU nanomedicine and precision medicine research networks;
  3. strengthen EU’s competitiveness and growth in nanomedicine and precision medicine through the translation of the consortium research and innovation outputs. The consortium will fulfill its goals through:
    • achieving research excellence;
    • providing a complete cutting edge research and innovation training program with some of the European top research institutes and industry partners;
    • hosting interdisciplinary and commercial workshops, seminars and outreach events;
    • maximizing knowledge transfer using Open Science and patents;
    • delivering highly trained professionals, whose profiles fit within the requirements of academia, industry and public/private institutions, fostering their employability and promoting the innovation of EU research.

NTSOL hosts ESR6 who will  participate in the design and development of DC magnetic field generator to create a magnetic field region where magnetic nanoparticles can be magnetically accumulated into osteosarcoma tumoral tissue. The magnetic field generator will accomplish regulatory policies concerning the magnetic field exposure safety considering future clinical perspectives.